Main Research Contents:

The study aimed to investigate the effect of infant starter formula containing the probiotic Bifidobacterium animalis subspecies lactis (Bb12) on intestinal immunity and inflammation.

Main Research Findings:

Infants consuming formula with Bb12 produced feces with detectable presence of Bb12 and augmented sIgA concentration. Furthermore, cesarean‐delivered infants consuming Bb12 had heightened immune response, as evidenced by increased anti‐rotavirus‐ and anti‐poliovirus‐specific IgA following immunization. These results demonstrate that negative immune‐related effects of not breastfeeding and cesarean delivery can be mitigated by including Bb12 in infant formula, thereby providing infants a safe, dietary, immune‐modulating bacterial introduction.

Holscher, et al.
Bifidobacterium lactis Bb12 Enhances Intestinal Antibody Response in Formula-Fed Infants: A Randomized, Double-Blind, Controlled Trial. 
JPEN J.Parenter.Enteral Nutr. 2012;36(1 Suppl):106S-17S