Main Research Contents:
The study sought to identify and characterize candidate probiotic strains capable of reducing pathogen reservoirs for the prophylaxis of rUTIs.
Main Research Findings:
L. plantarum strains CECT8675 and CECT8677 showed similar growth to L. rhamnosus ATCC55826 strain under simulated vaginal and intestinal conditions, but increased survival to simulated gastric conditions. A significant decrease in growth was observed for rUTI pathogens E. coli UPEC, P. mirabilis S. saprophyticus, K. pneumoniae and E. faecalis when co-cultured with the supernatants of candidate probiotic strains, both unadjusted and adjusted to the same pH as control media (pH 6). Finally, both L. plantarum strains showed a safe antibiotic resistance profile according to ISO 10932:2010 IDF 2010.
E. Simón, et al.
Screening of Lactobacilli strains of human origin, candidates for the prevention ofurinary tract infections.-1
Screening of Lactobacilli strains of human origin, candidates for the prevention ofurinary tract infections.-2
Ann Nutr Metab 2019;74(suppl 1):17–18